Sildenafil, or generic Viagra, is used to treat impotence or erectile dysfunction (ED).
A guy with Erectile Dysfunction will have trouble getting and maintaining an erection during sexual intercourse.
Some drugs, conditions, and foods may have harmful interactions with this medication.
When sildenafil and alcohol are combined, they can have serious negative effects.
As a result, doctors advise against mixing Viagra with alcohol.
Furthermore, excessive alcohol consumption, along with smoking, inactivity, and bad dietary habits, is one of the leading causes of male impotence.
This essay will explain why Sildenafil and alcohol should not be combined. But first, let’s acquire a better understanding of what Sildenafil is.
Sildenafil was the first drug licensed by the US Food and Drug Administration (FDA) for erectile dysfunction (ED).
Pfizer began producing it under the trade name Viagra in 1998, and a generic version was introduced in 2017.
Sildenafil is the active ingredient in both the generic and brand-name versions of this medication.
Take this prescription-only tablet 30-60 minutes before sexual activity. Nonetheless, its effects can last up to four hours.
How does Sildenafil function?
Sildenafil, like other erectile dysfunction drugs, inhibits Phosphodiesterase 5 (PDE5).
Sildenafil inhibits the PDE5 enzyme, which prevents the breakdown of cyclic Guanosine Monophosphate (cGMP).
Smooth muscle relaxation and vasodilation occur in the penile region as cGMP levels rise. Blood flow within the penis is increased as a result of this relaxation and dilation.
As a result, a guy can obtain and maintain an erection. However, sexual stimulation is required to achieve a hard erection.
What’s the connection between erections and alcohol?
An erection requires the activation of hormones, the brain, nerves, and blood vessels. However, excessive alcohol use can have a negative impact on all of these.
These functions are influenced by alcohol because it reduces the reaction of the brain’s Central Nervous System (CNS).
The CNS is responsible for transmitting information from the brain to the rest of the body.
The sensitivity of the penis decreases due to a lack of information transmission between the brain and the penis.
Furthermore, drinking lowers testosterone levels in men. Low Testosterone levels will further limit the production of Nitric Oxide.
In an erection, Nitric Oxide (NO) relaxes the smooth muscle, allowing blood to flow more freely.
The penile smooth muscle, on the other hand, cannot be relaxed if Nitric Oxide generation is impeded.
As a result, blood circulation to the penis is reduced, resulting in erectile dysfunction.
Sildenafil and alcohol interaction?
Interactions between Viagra and alcohol are common.
Side effects of Sildenafil (Viagra) such as nausea, headaches, chest pain, and nasal congestion are exacerbated by alcohol consumption.
Acute hearing loss, intraocular pressure (fluid pressure in the eye), heartbeat irregularities, and Priapism are all serious side effects of using Viagra or Sildenafil with alcohol.
Furthermore, drinking is one of the causes of erectile dysfunction. As a result, using Viagra with alcohol may reduce the medication’s effectiveness.
Other foods and beverages that may interact with Sildenafil, in addition to high-fat meals and grapefruit juice, include those high in fat.
High-fat meals may increase the time it takes Sildenafil to take action.
Sildenafil is effective and safe to use with moderate alcohol consumption.
Alcohol aggravates the negative effects of Sildenafil, such as headaches, flushing, dizziness, and eyesight problems. Excessive alcohol use raises the likelihood of experiencing these symptoms.
Alcohol may have no discernible influence on Sildenafil or its efficacy. It may, however, slow down several physiological functions, including achieving and maintaining an erection.
As a result, it is best to avoid combining Sildenafil and alcohol.