Vardenafil Vs Sildenafil: Which One to Buy?

When it comes to treating erectile dysfunction (ED), there are several prescription medications available on the market. Vardenafil and Sildenafil are two popular medications that are commonly prescribed for ED. Both medications belong to the same class of drugs called phosphodiesterase type 5 (PDE5) inhibitors and work by increasing blood flow to the penis to help achieve and maintain an erection.

However, despite the similarities, there are some key differences between Vardenafil and Sildenafil that should be considered when choosing which medication to buy.

How to Work

Vardenafil and Sildenafil work in similar ways to treat ED, but there are some differences in their mechanisms of action. Vardenafil has a more selective action on PDE5 compared to Sildenafil, which means it can achieve a similar effect at a lower dose. This makes Vardenafil a more potent medication than Sildenafil.

On the other hand, Sildenafil has a longer duration of action compared to Vardenafil. Sildenafil can remain effective for up to 4-5 hours, whereas Vardenafil can last for up to 6-8 hours. This may make Sildenafil a better option for men who need a longer-lasting medication.


The recommended starting dose for Vardenafil is 10 mg, which can be adjusted up to a maximum of 20 mg per day. For Sildenafil, the recommended starting dose is 50 mg, which can be adjusted up to a maximum of 100 mg per day.

It’s important to note that both medications should be taken at least 30 minutes before sexual activity, and only once per day. It’s also important to follow your doctor’s instructions regarding dosage and usage.

Side Effects

Both Vardenafil and Sildenafil are generally safe and well-tolerated medications. However, like all medications, they can cause side effects. The most common side effects of both medications include headache, flushing, and dizziness.

Other less common side effects of Vardenafil include back pain, indigestion, and nasal congestion. Sildenafil can also cause vision changes, such as blurred vision or changes in color perception. If you experience any side effects while taking these medications, talk to your doctor immediately.


The cost of Vardenafil and Sildenafil can vary depending on where you live, the pharmacy you buy it from, and whether you have insurance coverage. In general, Sildenafil is a more affordable option compared to Vardenafil.

However, it’s important to note that the cost of medication should not be the only factor to consider when choosing which medication to buy. Always consult with your doctor before starting any new medication to determine which option is best for your individual needs.

Read more: What’s the connection between Sildenafil and Alcohol?


Vardenafil and Sildenafil are both effective medications for treating ED. Vardenafil is more potent and has a more selective action on PDE5, while Sildenafil has a longer duration of action.

Both medications are generally safe and well-tolerated, but they can cause side effects. The cost of Sildenafil is generally more affordable than Vardenafil, but the cost should not be the only factor to consider when choosing a medication. Always consult with your doctor to determine which medication is best for you.

Check out Sildenafil medications: Vidalista 20 Cenforce 200 Vidalista 60 Cenforce 100


Is Vardenafil more effective than Sildenafil?

Yes, the effects of Vardenafil normally last 4 to 6 hours. Sildenafil, on the other hand, has an impact that lasts 3 to 5 hours.

How long does Vardenafil take to work?

Vardenafil takes at least 30 minutes to absorb and begin working.

It is, however, dependent on an individual’s health and other conditions. As a result, it is best to take this medication 30 to 60 minutes before sexual activity.

How long does Sildenafil take to work?

Sildenafil usually begins to work within 30 minutes. However, depending on circumstances such as high-fat meal consumption and an individual’s health, it can take up to an hour.

Vardenafil Vs Sildenafil Which is the best option?

Vardenafil, as well as Sildenafil are both drugs.

They are used for treating Erectile Dysfunction (ED) for males, or males assigned when they were born (AMAB). Sildalist 120  is a revolutionary professional treatment for erectile dysfunction.

Erectile Dysfunction refers to the inability to achieve and maintain an unshakeable erection.

Sildenafil was the initial drug that Food and Drugs Administration (FDA) was able to approve for treating ED. In contrast, Vardenafil was approved afterward.

Let’s look at the text to learn more about: Vardenafil vs Sildenafil and which one is the most suitable medication for you.

Basics of Sildenafil and Vardenafil

Sildenafil is, as we have mentioned is the very first FDA-approved medicine for impotence, also known as Erectile Dysfunction.

The active ingredient of Viagra and other generic Viagra medication is Sildenafil.

However, FDA approved Vardenafil in 2003, and it was introduced on the market under the brand name Levitra.

Sildenafil is also used for the treatment of Pulmonary Arterial Hypertension. However, Vardenafil is only used as an Erectile Dysfunction medicine.

Vardenafil and Sildenafil: How do they work?

Sildenafil and Vardenafil perform exactly the same way.

Both are part of the group of Phosphodiesterase kind 5 (PDE5) inhibitors.

PDE5 inhibition increases the concentrations of cyclic Guanosine Monophosphate (cGMP).

The increased cGMP levels relax the muscles of smoothness. Also, it dilates blood vessels that line that region called the penile.

Dialation of blood vessels helps to improve blood flow in the penile region.

The increase in blood circulation can aid a man or AMAB to achieve an erection.

But sexual stimulation is vital in order to get an erection.

What effects last longer? Vardenafil or Sildenafil

What effects are there for Sildenafil and Vardenafil are dependent on the health status of the individual.

The normal half-life for Vardenafil lasts 4-6 hours. In accordance with one article on some individuals its effects from Vardenafil can last as long as 8 hours.

Sildenafil’s half-life ranges from three to five hours.

This means that the effects be gone after 3 hours of having the Sildenafil pill.

While the difference isn’t massive, Vardenafil lasts a little longer than Sildenafil.

Which is more effective between Vardenafil and Sildenafil

The beginning of the actions in the two Sildenafil or Vardenafil is identical.

Both medicines begin to take effect after 30-minutes after consumption.

However, the health of an individual and other variables are also a factor in the speed at which the medicine will be effective.

If you ate a high-fat food prior to taking Sildenafil or Vardenafil, the initial onset of the action could be delayed. The active ingredient in Fildena 100 mg is sildenafil citrate which is part of a class of medicines known as phosphodiesterase type 5 (PDE5) inhibitors.

Vardenafil or Sildenafil absorption may be delayed by eating a diet high in fat.

Therefore, it is recommended to take these pills 30 to 60 mins prior to having an intercourse.

Which is more likely to cause negative side effects: Vardenafil or Sildenafil

Vardenafil and Sildenafil negative effects are quite common.

The most common adverse effects include:

  • Headache
  • Dizziness
  • Nausea
  • Flushing
  • Heartburn
  • Afraid stomach
  • Back back pain
  • Sleep issues
  • Runny or stuffy nose
  • Vision shifts
  • Lightheadedness
  • Unusual heartbeat
  • Breathlessness
  • Priapism

The side effects of headaches and stomach indigestion may persist even when the medication wears off.

Which is more efficient, Sildenafil or Vardenafil

Sildenafil and Vardenafil both work similar medically.

In the course of a study in which 92% of participants showed an improvement in their erections following drinking Vardenafil.

An additional investigation of Sildenafil Citrate showed 95% of males had better erections.

Thus each Vardenafil as well as Sildenafil are equally efficient in the treatment of Erectile Dysfunction in males.

They both boost supply of blood into the penile area which assists a person in getting an erection.

The time of onset for both medications takes about 30 minutes.

Which one is superior, Vardenafil or Sildenafil?

Sildenafil and Vardenafil both are well-known as efficient treatments to treat ED.

Vardenafil is more effective than Sildenafil. Fildena 150  mg, the strongest generic drug for the treatment of male erection problems, also known as erectile dysfunction (ED).

Both medicines work in just 30 minutes and cause similar side consequences.

Generic versions of both medications are available and are less expensive than brand name medicines.

Thus, Vardenafil has a little advantage over the other.

But, before taking any medicine you are prescribed, talk to your physician first.

Frequently asked questions

Does Vardenafil last longer than Sildenafil?

In general those effects caused by Vardenafil last from 4 to 6 hours. The effects of Sildenafil’s extend for up to 3 to 5 hours.

What is the time frame to allow Vardenafil to start working?

Vardenafil requires minimum 30 minutes to fully absorb and display its effects.However it is also contingent on the health of an individual and other elements. It is therefore recommended to take this medication between 30 and 60 minutes prior to sexual activities.

How long will it take for Sildenafil to take effect?

Sildenafil usually begins to work in about 30 mins. However, depending on the certain factors such as the consumption of meals with high fat content and the health of an individual it could take as long as 1 hour.

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